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Nutrients 14:2559

However, genetic ablation of either glucose uptake or fatty acid oxidation in osteoclast precursors using LysmCre results in moderate sexually dimorphic bone phenotypes in vivo, suggesting other metabolic pathways play a more dominant role (Kushwaha et al, 2022

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Copper ions bound at two sites separated by an 11 aqueous cleft participate in the two single electron transfer steps needed to generate a peptidyl--hydroxyglycine product (Grechnikova et al., 2020)

Strategies to modulate ROS levels include the use of antioxidants, ROS scavengers, and inhibitors of ROS-generating enzymes