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This subcellular localization enables the direct protection of mitochondrial lipids, proteins, and mtDNA from oxidative damage, a critical advantage in diseases like neurodegeneration and metabolic disorders

This indicates that polyP concentration in cardiac myocytes is variable and depends on levels of energy substrates and the degree of coupling of the mitochondrial respiratory chain

Pain 161(Suppl 1):S65-s86

doi: 10.1038/nm.4021 104 WarburgOWindFNegeleinE

Cardamonin, a natural chalcone from Alpiniae katsumadai , inhibits breast cancer cell growth by suppressing HIF-1 through blockade of the mTOR pathway and inducing metabolic reprogramming characterized by reduced glucose uptake and lactate transport 191