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Active Skin Conditions: Avoid applying copper peptides to areas with active infections, open wounds (unless specifically for wound healing under medical supervision), or severely compromised skin barrier until these conditions resolve

Even the success of a few approved drugs provides only minimal patient improvement

Sleep quality is tracked before, during, and after the 10 day pulse so the cycle is evaluated objectively

The evidence for DSIPs effectiveness in chronic insomnia is still inconclusive

During the meeting, FDA staff scientists highlighted a general lack of quality data supporting safety and effectiveness