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Clinical signs are indistinct and include lethargy, depression, ataxia, anorexia and intermittent vomiting, and in severe cases, can induce neurological disease and blindness in cats

It is unknown whether or not the patients included in the analysis maintained a healthy diet and exercise regimen, which can help mitigate bone density loss

This effect results from Depo-Proveras suppression of ovulation combined with thinning of the endometrial lining , making bleeding less likely to occur