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However, its mechanism of increasing GH and IGF-1 can cause downstream effects that mimic elevated growth hormone levelsespecially at higher doses or with long-term use

In its May 2026 evaluation, the FDA identified one small meeting abstract describing a short randomized study in people with ulcerative colitis

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Sugerman HJ, DeMaria EJ, Kellum JM, Sugerman EL, Meador JG, Wolfe LG

The Ac-SDKP Fragment and Derivative Studies Beyond thymosin beta-4 and TB-500, the tetrapeptide fragment Ac-SDKP (acetyl-seryl-aspartyl-lysyl-proline), also known as goralatide, represents another bioactive derivative of the thymosin family