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Analytical scales, calibrated instruments, and controlled dilution processes are essential for maintaining consistency

In addition, simvastatin increased the expression of co-stimulatory molecules, production of IL-1 and IL-12p70, apoptosis, and autophagy in Mtb-infected monocytes (143)

With advanced mass spectrometry and RNAseq-based approaches that allow to study different posttranslational modifications as well as mRNA abundance and splicing, it should become feasible to map the transcriptional and posttranslational regulation of cargo proteins and their associated endocytic factors upon different stress conditions and to delineate the underlying signaling pathways

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ME2 is localized in the mitochondria, whereas PFK is localized in the cytosol (Fig