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In yet another study, researchers found that cigarette smoke prevented glutathione from reducing, therefore preventing it from performing its antioxidant duties as the reduced form of glutathione is the active form

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doi: 10.1038/s41564-017-0089-z, 89 Shen-GuntherJ.XiaQ.CaiH.WangY

The reported variants and small indels were annotated with the most severe entry by the Variant Effector Predictor 58 based on The Sequence Ontology term ranking 59