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Thus, the major metabolites of paracetamol at the therapeutic dose level are: paracetamol sulfate, paracetamol glucuronide, paracetamol L-cysteinyl conjugate [more exactly 3-(L-cysteinyl)-4-acetamidophenol] (PLCC) and paracetamol N-acetyl-L-cysteinyl conjugate [more exactly 3-(N-acetyl-L-cysteinyl)-4-acetamidophenol] (PNALCC) (Nicholls et al ., 1997)

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PMID: 39245317 Sci RepLMK-235 suppresses osteoclastogenesis and promotes osteoblastogenesis by inhibiting HDAC4

Increasing DHODH expression or inhibiting its degradation rate has become an effective way to inhibit ferroptosis