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Available from: [DOI] [PubMed] [Google Scholar] 109.Deas E, Cremades N, Angelova PR, Ludtmann MHR, Yao Z, Chen S, et al

In this paper, we investigate the impact of reducing agents on protein synthesis in a reconstituted cell-free protein synthesis system ( PURE system , Product name: PURE frex )

5-oxoproline is converted to glutamic acid by the enzyme 5-oxoprolinase

When cellular SAM concentrations are high, as would be expected after a meal containing protein (and thus methionine), SAM activates cystathionine -synthase and inhibits the synthesis of 5-methyltetrahydrofolate by MTHFR