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MarchiPHVendraminiTHAZafalonRVAde PrncipeLACesarCGLPeriniMPet al

DOI: 10.1024/0300-9831.75.1.3 Spiering, B

In addition, current research on saponin-chemotherapeutic combination therapies remains fragmented, with inconsistent research focuses across different saponins and chemotherapeutic agents, and a lack of systematic exploration into their synergistic mechanisms

Existing studies predominantly use cyclophosphamide to establish non-tumor-bearing immunocompromised mouse models, and only verify the restorative effects of saponins on immune organs, immune cells, and cytokine production [114,115,116]