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The autocrine IL-8 loop enhances neutrophil recruitment and activation in severe AH, sustaining liver inflammation through p38 MAPK activation [75]

Oxidative cleavage of the disulfide bond of cystine by allyl isothiocyanate

Also addition of solution of glutathione (GSH) transferase in the reaction mixture caused a marked increase in the rate of reaction compared to the non-enzymatic, showing monobromobimane was a substrate for this enzyme ( Figure 1 )