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Combining network pharmacology and transcriptomic strategies to explore the pharmacological mechanism of Total Ginsenoside Ginseng Root and its impact on antidepressant effects

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Introducing NO to the resulting radical system led to an addition reaction on the S-atom towards the formation of GSNO

The present review thus focuses on the role of GPX4 in the myeloid lineage, describing how increase in GPX4 expression can impact on myeloid cell homeostasis and transformation and whether GPX4 inhibition could represent an attractive strategy to treat AML patients