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cGAS, cyclic GMP-AMP synthase

found that repression of NRF2 antioxidant pathways served as a driver mechanism for the genetic premature aging disease Hutchinson-Gilford progeria syndrome (HGPS) [115], which is caused by constitutive progerin production, a mutant version of the nuclear protein lamin A

C., Ohno, S., Tamaoki, T

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Studies in older adults show that restoring more youthful GH levels through secretagogue use can reverse some age-related changes including improved body makeup, enhanced bone density, better skin quality, improved cognitive function, and enhanced overall vitality