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Diabetes & Endocrinology

Evaluation of genome-wide loci of iron metabolism in hereditary hemochromatosis identifies PCSK7 as a host risk factor of liver cirrhosis

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demonstrated that mice given oral glutathione showed increased concentrations in kidney, heart, lung, brain, and small intestine within one hour

In addition, the likelihood of developing NASH increases with the severity of obesity.11,36 There is a universal association between NASH an insulin resistance regardless of body mass index, suggesting that insulin resistance is a central factor in the pathogenesis of NASH.38 The elevated expression of TNF-a in the liver seen in NAFLD can represent a link between the development of insulin resistance and hepatic steatosis