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Si-Wu-Tang attenuates hepatocyte PANoptosis and M1 polarization of macrophages in non-alcoholic fatty liver disease by influencing the intercellular transfer of mtDNA

Rab1-dependent ER-Golgi transport dysfunction is a common pathogenic mechanism in SOD1, TDP-43 and FUS-associated ALS

Analogously, magnesium is an essential cofactor for the autophosphorylation of insulin receptor tyrosine kinasea process directly associated with enhanced insulin sensitivity, which further triggers the downstream PI3K/AKT signaling pathway and induces the translocation of GLUT4 to the cell membrane, enhancing cellular glucose uptake and regulating blood glucose levels (107)

A.StamelouM.GoetzC

Our data reveal progressive metabolic remodeling associated with neuronal maturation, including enhanced oxidative phosphorylation, increased mitochondrial content, and respiratory capacity