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Results G-CSF significantly reduced cardiomyocyte apoptosis in the diabetic myocardium in vivo and led to an increase in Beclin-1 level and the LC3-II/LC3-I ratio, and decreased P62 level

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One small study (25 people) found collagen reduced nail brittleness, but it had no placebo group for comparison

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Case studies, case series, and secondary data sources (eg, literature reviews) were included in this review as supplemental information and were discussed within the synthesis of the evidence but were not considered in the weight-of-evidence determinations

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