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A novel neurotrophic property of glucagon-like peptide 1: a promoter of nerve growth factor-mediated differentiation in PC12 cells

Our data pointed out a positive correlation between KYN/TRP or QUIN/TRP ratios and the gravity of depressive symptoms, supporting those data reporting increased QUIN and KYN fluxes associated with severity of depression and presence of suicide thoughts/attempts (61, 62)