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Tranexamic acid (when included) adds a further dimension by inhibiting melanin synthesis through a mechanism that is independent of glutathione

75 In contrast, obesity induces a shift toward classically activated macrophages (M1), which secrete pro-inflammatory cytokines such as IL-1, IL-6, and TNF-

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At these doses, the most common side effects of NAC are nausea and vomiting, although severe allergic reactions can occur in susceptible individuals (Ferner 2011)

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