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Controlled-release studies showed release of 45.8% coumarin over seven days, indicating sustained release

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Arbutin w/o/w nanoemulsions that were co-encapsulated with coumaric acid showed enhanced encapsulation efficiency, increased drug stability, sustained drug release, and improved skin delivery in comparison to the free drug (Wen et al., 2006a

Itulah cara untuk meningkatkan kadar glutathione dalam tubuh