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It is required as a cofactor of cytosolic and mitochondrial enzymes that are directly or indirectly involved in energy metabolism

Nanoparticles can be engineered to cross the BBB via receptor-mediated transcytosis or adsorptive-mediated transcytosis, or to bypass the BBB altogether through alternative routes such as intranasal delivery, as described in-depth in Section 4.3

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The research points toward a strong "yes" in terms of general support for cardiovascular wellness

These findings suggest that both DPP-4i and GLP-1RA elicit pleiotropic tubular protective effects and may serve as another potential therapeutic strategy options to benefit patients with DKD