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Pan Y, Tian T, Park CO, et al

Tumor necrosis factor identified in multiple sclerosis brain

When the xenograft volumes were ~50 mm 3 , the mice in all six groups were treated with 100 L of saline buffer or TRAIL (5 g/kg/day) by intraperitoneal injection three times a week for 45 days, and tumor growth was monitored as described above

This difference could be due to the fact that DEM decreases both nuclear and cytosolic glutathione levels in opposition to BSO, which only decreases cytosolic glutathione as it is shown in figure 4C