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[13] [14] Some historical or research protocols have used much higher doses (e.g., 250 mg/kg as a single IV bolus in diagnostic growth-hormone testing), but such regimens are uncommon outside controlled studies

The in vivo administration of GPx1 to dopaminergic neurons decreases the toxicity of 6-hydroxydopamine in Parkinsons disease

& Merril, G.F

Although the two are different physiological regulatory methods for cells facing various stresses, increasing evidence shows that autophagy and ferroptosis are closely related, and certain selective autophagy forms can regulate ferroptosis through modulating intracellular iron storage and oxidative stress levels

Riedemann, J