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Overall, the evidence base is promising, the safety profile is encouraging, and clinical outcomes especially under properly designed protocols can be significant

Possible side effects include: Mild injection site discomfort (if administered subcutaneously)

These differences likely reflect local tissue binding, lymphatic uptake, and first-pass metabolism variations between administration sites and species

A recent study by Jeon and colleagues showed that senescent chondrocytes accumulate around traumatic cartilage lesions and are associated with the development of arthritis

This may vary depending on how heavy their menstrual flow is, but in general, they might find they need extra rest during these points in their cycle