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TGA Chief Medical Advisor Robyn Langham says that's because compounded medications are exempt from the agency's usual checks and balances

Vitamin B12 is found in animal produce including meat, fish, milk, cheese and eggs plus fortified foods such as some breakfast cereals and plant milks

In addition, the concentration of 5MTHF in the CSF is lower than normal in patients with idiopathic cerebral folate deficiency, and some patients also have reduced concentrations of CSF 5-hydroxyindoleacetic acid and biopterin