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PloS One (2017) 12:e0188123

Over 42 days, the ethanol group received 20% ethanol in their drinking water, while losartan was administered intraperitoneally at doses of 1 mg/kg and 3 mg/kg to the treatment groups.The results demonstrated that losartan significantly reduced oxidative stress markers, evidenced by decreased levels of malondialdehyde and increased total thiol levels in renal tissues

ACE2 is expressed in most human tissues and cell types as a type I integral membrane protein solubilized by the action of a disintegrin and metallopeptidase (ADAM)-17 293

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