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These metabolites were mainly enriched in 18 pathways, of which riboflavin metabolism, phenylalanine, tyrosine and tryptophan, ubiquinone and other terpenoid quinone, vitamin B6 metabolism and phenytalanine metabolism were significantly enriched ( Figure 6D )

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The mean of measurements on two adjacent CT slices at L3 level was used to calculate the L3 skeletal muscle index (L3 SMI) by correcting it for height