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A number of studies have demonstrated that mitochondrial integrity declines as a function of age

In healthy blood vessels, ECs exhibit low metabolic activity and remain in a quiescent state that is stable and maintains the vascular integrity, regulates permeability, and prevents unnecessary clotting and inflammation [19, 20]

Boroujeni ME, Simani L, Bluyssen HAR, Samadikhah HR, Zamanlui Benisi S, Hassani S, Akbari Dilmaghani N, Fathi M, Vakili K, Mahmoudiasl G-R, Abbaszadeh HA, Hassani Moghaddam M, Abdollahifar M-A, Aliaghaei A (2021) Inflammatory response leads to neuronal death in human post-mortem cerebral cortex in patients with COVID-19

Toxicol Appl Pharmacol 134:273284 Winterbourn CC, Metodiewa D (1994) The reactions of superoxide with reduced glutathione

To view a copy of this license, visit About this article Cite this article Ramkumar, K., Samanta, S., Kyani, A