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The requestor suggested the following two options for MS-DRG assignment updates: (1) reassign cases describing the insertion of a neurostimulator generator into the skull in combination with the insertion of a neurostimulator lead into the brain (including cases involving the use of the RNS neurostimulator) from MS-DRG 023 to MS-DRG 021 with a change in title to Intracranial Vascular Procedures with PDX Hemorrhage with CC or Craniectomy with Neurostimulator; or (2) extract all cases from MS-DRG 023 involving a craniectomy/craniotomy with device implant and create a new MS-DRG for these cases

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Strong similarities in gene expression profiles between ndufs2 -/- larvae and both human fibroblast and worm CI structural subunit nuclear gene disease models demonstrate the utility of using our model to understand underlying genetic perturbations caused by PMD and the effects of potential therapeutics ( Figure 6 )

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