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The upregulation of PDI in ALS suggests that a cellular defensive mechanism is triggered against redox dysfunction

Fourth, DN involves multiple regulated cell-death pathways with potential crosstalk, and since apoptosis-related proteins (such as the caspase family) and autophagy markers (such as LC3 and p62) were not assessed, it cannot be excluded that DAPA also modulates these pathways and contributes to the observed protective effects

mercury and lead generate well-defined and different neurobehavioral syndromes

10.1093/carcin/21.3.361 94 MaynardR

Morganroth PA, Lim HW, Burnett CT (2013) Ultraviolet radiation and the skin: an in-depth review