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The Neelakantan 2018 study in Biochemical Pharmacology reported that 5-Amino-1MQ administration to C57BL/6 mice on a 60% kcal-from-fat high-fat diet produced concentration-dependent reductions in fat mass and adipose-tissue NNMT enzymatic activity without significant changes in lean mass or food intake [1]

mice in the Ctrl group received 50 L of 0.9% NaCl via the same procedure

Once treatment is initiated, your GP will typically arrange follow-up appointments to monitor your response to treatment

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