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Because iodine is critical for normal development of the brain, deficiency of this mineral during critical periods, such as during fetal development or during early childhood, can have deleterious effects on cognition

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Hence, pharmaceuticals that target the NRF2 pathway can influence multiple pathways involved in the neurodegenerative process, and therefore hold potential to become therapies that can significantly modify the course of neurodegenerative diseases

FIGURE 20 A number of platinum(II) complexes derived from curcumin exhibit micromolar cytotoxicity and interesting photoactive properties