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(2025) 328:C100C112

In some cases, curcumin can even restore fluconazole susceptibility in resistant Candida strains

Specifically, abnormal DNA methylation patterns contribute to amyloid-beta (A) and phosphorylated tau protein aggregation, thereby fostering plaques and tangles formation (159)

GST P1-1, GST M1-1 and GST A1-1 have been shown to catalyze the inactivation process of , unsaturated carbonyls like acrolein, (a cytotoxic compound present in tobacco smoke), propenals, (generated by oxidative damage to DNA) and alkenals, (formed by oxidative damage to lipids) [25], [70]

We use the model system Drosophila, where virtually every gene can be targeted for knock-out or activation in a cell type selective manner Drosophila also offers the advantage that its brain is composed of a relatively small number of stereotyped neuronal lineages, groups of neurons descended from individual embryonic stem cells, called neuroblasts