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It is also utilized in various metabolic pathways and redox homeostasis, as it is used for the component of major endogenous antioxidant glutathione and the generation of sulfur-containing biomolecules

Results also depend on lifestyle, exposure, diet, and genetics

However, there are many questions that remain to be answered

Labile plasma iron in iron overload: redox activity and susceptibility to chelation [J]

Curcumin is often described as a hormetic compound because it induces an adaptive stress response: it mildly stresses cells in ways that activate Nrf2 and other transcription factors, leading to increased production of antioxidant and cytoprotective proteins (e.g., heme oxygenase-1) that precondition cells against subsequent injuries (77, 78)