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Discontinue ketorolac if clinical signs and symptoms consistent with liver disease develop or systemic manifestations (e.g., eosinophilia, rash) occur (2,3)

Talk with a qualified clinician and consult legal counsel for compliance decisions

glutathione doesn't exhibit tolerance or receptor downregulation

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One intriguingbut speculativepossibility is that GSSG might paradoxically protect the ER by exacerbating protein misfolding, if doing so renders misfolded client proteins more readily recognized and either refolded or cleared rather than futilely engaged with the ER quality control machinery