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Samples were incubated at room temperature for 1 h, vortexing intermittently, and then quenched by the addition of hydroxylamine (5 L of 5% w/v in HPLC water per sample) and incubated for 15 min at room temperature

OH reacts with purine and pyrimidine bases in DNA and RNA ( OH attacks thymine or deoxyguanosine bases to generate 5-hydroxy-6-hydrothymine or 8-hydroxy-2'-deoxyguanosine (8-OHdG)

Die Behandlung mit menschlichem Wachstumshormon hat bei Erwachsenen, die einen Wachstumshormonmangel aufweisen, optimistic Ergebnisse bei der natrlichen Behandlung von Fettleibigkeit gezeigt

At the same time, however, it should be strongly stressed that no real iodine-dependent danger is associated with iodized salt consumption or additional iodine prophylaxis at preconception, during pregnancy and postpartum (also in hypothyroid women) and that to resign from such kinds of iodine prophylaxis would be not only unjustified but could be even harmful in consequence

& Smith, C