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doi: 10.1016/j.xhgg.2021.100069 12 GillDEfstathiadouACawoodKTzoulakiIDehghanA

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Structure-Activity Relationship (SAR): The backbone is derived from GIP but modified to introduce Glucagon activity

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The detoxification of BaP is usually associated with the production of highly reactive intermediate compounds as BaP-quinones which can react with cellular components leading to excessive ROS generation, reducing the antioxidant capacity and oxidative damage (Derakhshesh et al

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It claimed 'GLP-1s for diabetes could be sold at a profit for just US $0.89 per month, compared to the price of $95 per month charged in Brazil, $115 per month charged in South Africa, $230 charged in Latvia and $353 charged in the US, which is a 39,562% markup over what the estimated generic price could be.' Christa Cepuch, Pharmacist Coordinator at MSF's Access Campaign, argues 'These new drugs are an absolute game changer for people living with diabetes, but are being kept out of the hands of hundreds of millions of people in low- and middle-income countries who need them' (Barber, Gotham, Bygrave

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