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BCAAs, especially leucine, could be signaling molecules that are directly responsible for the pathophysiology of heart disease

Mitochondrial damage induced by conditions of oxidative stress

Salt-sensitive hypertension in mitochondrial superoxide dismutase deficiency is associated with intra-renal oxidative stress and inflammation

It could be speculated that excessive intake of leptin during lactation might not provide greater protection against excess weight gain or could even favour the development of leptin resistance later in life, although these possibilities have not been specifically addressed

By reducing the risk of apoptosis, Se helps preserve the functional capacity of thyroid tissue and encourages its regeneration [97]