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Zhang et al., 2017

Blood pharmacokinetics and biodistribution of T-AsiG-CPL in vivo Encouraged by the effective PDAC cell growth inhibition and PSC quiescence in vitro, we further investigated the pharmacokinetics and bio-distribution of T-AsiG-CPL in an orthotopic pancreatic tumor mouse model, which was established by co-inoculation of mice with T3M4-luci cells and PSC that has been demonstrated to closely resemble human pancreatic cancer by generating desmoplastic stroma 29,30

The findings suggested that the anti-aging effects of CASIN were facilitated by 60S ribosomal protein L4 (RPL4), which played a role in collagen synthesis and influenced fibroblast cytoskeletal morphology (Haydont et al., 2019)

[DOI] [PubMed] [Google Scholar] Shapiro S

In order to properly determine aggregate payments on each side of the comparison for budget neutrality, prior to FY 2014, we included estimated Medicare DSH payments on both sides of our comparison of aggregate payments when determining all budget neutrality factors described in section II.A.4