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Based on this data, we calculated a December 2021 national average case-weighted CCR of 0.235395 and a December 2022 national average case-weighted CCR of 0.229631

Vozza et al., 2018

Tramadol and tapentadol are centrally acting analgesics that are used for moderate-to-severe neuropathic pain, with tapentadol offering greater potency and fewer gastrointestinal side effects [115]