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doi: 10.1016/s0012-1606(03)00212-4 62 SweereU.EichenbergK.LohrmannJ.Mira-RodadoV.BaurleI.et al

doi: 10.1016/S0002-9440(10)63667-X

24 The remaining portion, constituting two-thirds of the protein structure, is composed of the distinct all--helical region, which forms the C-terminal domain of GSTs

Doing so can increase the risk of serious side effectsfor example, fat-soluble vitamins (such as vitamin A, vitamin D, vitamin E, and vitamin K) can accumulate in the body over time, reaching toxic levels

Therefore, in this review, we provide an overview of the mechanisms of vitiligo-associated oxidative stress and the most commonly studied antioxidants, describe the proposed mechanisms of action, and discuss the underlying evidence for their use or ineffectiveness