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First, they must be transported to the mitochondria where the enzymes of -oxidation are located and fatty acids are oxidized, as there is only a minimal contribution from the peroxisomal system for which the preferred substrates are very long-chain fatty acids

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Malaguarnera, M., Vacante, M., Giordano, M., Motta, M., Bertino, G., Pennisi, M., Neri, S., Malaguarnera, M., Li, Volti G., and Galvano, F

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Unlike harsh stimulants or short-term fat burners, it works by addressing the core barrier to fat loss and fatigue: poor cellular transport and energy production