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Therefore, it can elicit its antioxidant action in both the cytosol and plasma membrane in contrast to vitamin C (which is lipophobic) and vitamin E (which is lipophilic)

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OH is the most dangerous free radical and major culprit in free radicalmediated toxicity in cells.16, 3 Both O2 and OH can individually act on lipid membranes to promote the formation of lipid radical (L) which in the presence of oxygen is capable of generating lipid peroxy radical (LOO)3 (Fig

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