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Several methods are commonly used to detect and quantify thiols: Spectrophotometric Methods : Thiols react with specific reagents like Ellmans reagent (5,5'-dithiobis(2-nitrobenzoic acid) or DTNB), producing a yellow-colored product that can be quantified using UV-Vis spectroscopy

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10 proposed that the detoxification of succinicGSH mediated by GR explains the enhanced oxidative stress in FH-deficient cells