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doi: 10.3390/antiox11010125 40 Gonzalez-LiencresCTasCBrownECErdinSOnurECubukcogluZet al

Finally, molecular docking analysis using AutoDock Vina 1.1.2 and Amber14 identified binding sites between MSL1 and Erastin, as shown in Fig

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Furthermore, this study goes beyond computational analysis by integrating in vitro experiments (CCK8, EdU, flow cytometry, and qPCR), systematically validating the effects of oxidative stress on the expression of key cataract genes (DKK3 and GSTM1) and the biological behavior of lens epithelial cells, thereby enhancing the biological credibility and translational significance of the findings