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Several factors contribute to this damage

Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

This can lead to inaccuracies in estimating an individuals risk

These include glutathione S-transferase (GST), UDP-glucuronosyltransferases (UGTs), and quinone oxidoreductase (NQO1)all of which play key roles in transforming fat-soluble toxins into water-soluble compounds that can be excreted through bile and urine

Lower resolution population data were taken from HYDE 3.2 which includes annual data for the year 1990 and for the years 20002015 with a resolution of 5 arc-min