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That said, our thinking when we developed these approaches was shaped by the form and nature of the Advanced APMs that existed at that time

It has been demonstrated to upregulate the expression of tight junction proteins (e.g., ZO-1, occludin) and prevent their degradation following I/R injury

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Overlap statistics were higher (range 0.600.70) when comparing PRO measures in patients with high versus low BSA involvement, indicating that a randomly selected patient with high BSA involvement would have at least the same or greater impairment in quality of life and symptom burden as a patient with low BSA involvement in 6070% of comparisons