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doi: 10.1002/art.1780400113 64 CaoTZhouJLiuQMaoTChenBWuQet al

Fatty liver, also known as non-alcoholic fatty liver disease (NAFLD) or non-alcoholic steatohepatitis (NASH), occurs when the excess fat builds up in the liver

Consistent with a disabled lipid peroxidation defense, we observed that after one hour of GPX4 inhibition and prior to any cell death, there is a drastic elevation in 2,7-dichlorofluorescein (DCF) staining of ROS which indicates lipid peroxidation in persister cells but not parental cells (Fig