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Marriage of scintillator and semiconductor for synchronous radiotherapy and deep photodynamic therapy with diminished oxygen dependence

Availability of data and materials All data generated or analyzed during this study are included in this published article (tables and figures)

Glutamate surges to toxic levels

Importantly, matrix stiffness can activate the epithelial to mesenchymal transition (EMT) program, resulting in a partial EMT state [79], which is distinguished by the simultaneous presence of both epithelial and mesenchymal traits, enabling a more efficient collective cell migration and invasion [80]

When an oxidative stressor or electrophile interacts with the Keap1-Nrf2 complex, it allows for the release and subsequent nuclear accumulation of Nrf2 through a complex process of ubiquitination-inhibition, thus triggering an anti-stress response by the cell