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Copper is an essential trace element that participates as a cofactor in numerous enzymes (including superoxide dismutase, cytochrome c oxidase, and lysyl oxidase) and in regulatory roles where its redox activity and metal-binding properties become biologically consequential

Huang KJ, Feng L, Wu P, Liu Y, Zhang L, Mi HF, et al

pH dependent catalytic activities of platinum nanoparticles with respect to the decomposition of hydrogen peroxide and scavenging of superoxide and singlet oxygen

, their team used in situ polymerization to develop a unique multi-responsive microgel [304]