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It has been demonstrated that aldosterone stimulates superoxide radical formation in endothelial cells by activating Rec1 (71)

In summary, growing evidence underscores that gut microbiota dysbiosis plays a pivotal role in both the development and outcome of ischemic stroke through immune, barrier, and metabolic pathways, suggesting that restoring gut microbial balance could become an essential strategy for stroke prevention and recovery

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Economies of scale may be limited for peptide drugs treating rare conditions, where small patient populations cannot support large-scale manufacturing investments